Rare diseases
breakthrough research
Small questions. Rigorous analysis. Continuous new knowledge.
LearnRare is a continuously expanding research portfolio that utilises AI-accelerated research to answer unexplored questions in rare diseases.
Question
Focused knowledge gap
Evidence
Public datasets & literature
Analysis
Computational methods
Contribution
Short research report
What's new
The latest published research, most recent first.
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RD-002
RD-002 — Multidomain Longitudinal Prediction of Functional Decline in Amyotrophic Lateral Sclerosis: Cross-Domain and Psychosocial Predictors Beyond Baseline Function
Longitudinal modelling across 143 ALS patients finds that hand-use and speech scores help predict other abilities later on, while feelings of hopelessness repeatedly stand out as a predictor across nearly every ability and time point.
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SEPTEMBER 2026
RD-001 — Pathway-Level Characterisation of Peripheral Blood Transcriptomic Dysregulation in Spinal Muscular Atrophy
Differential expression and pathway enrichment analysis of whole-blood RNA-seq recovers SMA's core molecular lesion — SMN-associated nuclear structures — directly from blood.
What we do
Rare disease research is often underrepresented or underfunded, and faces challenges like limited datasets, small sample sizes and fragmented evidence. LearnRare utilises modern advancements and latest technologies in AI, particularly LLM agents, to investigate specific questions through computational modelling, data analysis and literature reviews, contributing to expanding our knowledge of these rare conditions. By presenting our findings in an accessible manner and engaging social media platforms, we hope to reach a wider audience and spread awareness for those with rare diseases who are often neglected.
AI-driven
Involving AI technology to enhance the depth, complexity and efficiency of our research output.
Accessible
Communicating complex scientific findings using engaging visuals and concise summaries.
Awareness
Using online presence to reach larger audiences and spread awareness for rare diseases.
A different research model
The value of LearnRare comes from its unique research model.
Conventional research process
LearnRare model
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with AI-integration throughout
Follow the research
Short-form breakdowns of research questions, procedures and findings.
Research library
The complete archive of LearnRare's research projects.
No jargon, no assumed knowledge
Decoded
The same research, explained the way we'd explain it to a friend. Skip the statistics — get the story.
About LearnRare
LearnRare exists because rare-disease research is uniquely challenged by underrepresentation in research, small patient groups, low data availability and the lack of awareness in both the research community and the general public. Consequently, rare disease research often moves slowly, resulting in fewer innovations reaching those affected and causing systemic inequities that remain unaddressed.
To contribute to improving rare disease research, we follow our 3 core objectives:
Firstly, we utilise the incredible computational power of cutting-edge AI innovations to drive investigations, producing new knowledge more efficiently whilst adhering to a high scientific standard.
Secondly, we aim to improve the accessibility of our findings to appeal to broader audiences, such as students or budding health professionals, those living with rare diseases or their family members, and even established researchers and medical professionals. We do this by presenting our findings using short, concise reports with engaging visuals rather than long conventional academic papers - designed to be understood, not just published.
Thirdly, we combine our rapidly growing research portfolio with social media engagement and presence, sharing our results with a broader public audience. This allows us to promote awareness for rare diseases and contribute to addressing the inequities that exist.
AI-driven, accessible and improving awareness - we strive to make a real impact in rare disease research, one step at a time.
Contact
learnrare@yahoo.comResearch interests
Every rare disease out there.
The diseases that we are currently aware of and looking to investigate include:
- Charcot–Marie–Tooth disease (CMT)
- Motor neurone disease (MND)
- Muscular dystrophy (MD)
- Neuromyelitis optica spectrum disorder (NMOSD)
- Orthostatic tremor (OT)
- Spinal muscular atrophy (SMA)
If you would like to suggest a topic or condition, please contact the email address below.
Follow the research
Research findings and visual explainers, in shorter form.